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Rapid Efficacy of Low Carbohydrate Diet for Diabetic Patient by Use of FreeStyle Libre

Tetsuo Muneta, Eri Kawaguchi, Miho Hayashi, Hiroshi Bando and Koji Ebe

In recent years, continuous glucose monitoring (CGM) has been introduced and used in clinical diabetic research.
Authors have investigated research about Low Carbohydrate Diet (LCD) and Calorie Restriction (CR) and developed
medical and social LCD movement through Japan LCD Promotion Association (JLCDPA). In this study, a case with
remarkable improving effect for change from CR to LCD is presented using CGM. The case is 41 years-old female
with type 2 diabetes mellitus (T2DM). She was newly diagnosed as T2DM with HbA1c 11.0%, glucose >400 mg/dL,
BMI 26.0, AST 30 IU/mL, Hb 16.3 g/dL. She was given CR meal with 60% carbohydrate on day 1 to 4, and LCD
meal with 12% carbohydrate on day 5 to 7. Daily profile of blood glucose showed 200-400 mg/dL in day 1-4,
160-240 mg/dL on day 5 and 110-150 mg/dL on day 7. FreeStyle Libre (Abbott, USA) has been valid and useful
medical apparatus for monitoring the the detailed fluctuation of blood glucose. Blood glucose value was immediately
decreased just after starting LCD, and the short-term effect of the LCD was found. These results would become
basal and reference data and contribute to the development of future research.