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Neonatal Purpura Fulminans in Neonate with Severe Congenital Protein C Deficiency: Case Report

Avantika Chauhan, Stuti Shukla, Tanvi Agrawal, Shalini Tripathi, Mala Kumar

Neonatal purpura fulminans is a rare life threatening condition caused by congenital or acquired causes. The condition is fatal so prompt diagnosis and management is important. It presents as acute disseminated intravascular coagulation and haemorrhagic skin necrosis and requires judicious use of anticoagulant therapy. Here we describe a case of neonatal purpura fulminans due to congenital protein C deficiency presenting late with haemorrhagic and necrotic skin lesions, anemic retinopathy and cystic encephalomalacia, managed with fresh frozen plasma transfusions and low molecular weight heparin.